Lysosomes
Author | : Frederick R. Maxfield |
Publisher | : John Wiley & Sons |
Total Pages | : 586 |
Release | : 2016-06-22 |
ISBN-10 | : 9781118978313 |
ISBN-13 | : 1118978315 |
Rating | : 4/5 (13 Downloads) |
Book excerpt: Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. • Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates • Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair • Introduces new pathways in therapeutic development and new mechanisms in drug development