Journey Through the World of Malaria

Book excerpt: Our understanding of the pathogenic mechanisms of the malaria parasite has accumulated over the years with the advent of genomic knowledge playing a crucial role. Although great strides have been made in the field of malaria research, malaria still remains one of the most important public health issues in the world. Years ago, malaria was eradicated in some countries but global warming is playing a part in the spectacular re-emergence of malaria in some of these countries. There is still no effective vaccine, although some research has provided interesting data and anti-malaria drug resistance is the time bomb that has the potential of detonating the field of malaria research. Funder fatigue is now derailing the progress made over the years, which makes the field of malaria research look a bit gloomy. This book reviews the most important findings associated with malaria research over the couple of years with a timely overview. The topics covered include historical perspectives of the field of Malariology, life cycle of the parasite, recent advances in the epidemiology of malaria, pathogenesis with sub topics such as the parasite and immune system, virulence factors and clinical manifestations analysed in detail. The updated anti-malarial drug treatment, development and resistance are also discussed in detail. Finally, the social and economic burdens of malaria are looked at and various potential control strategies are put forward. This book will be essential to everyone interested in infectious diseases.