FISH Technology
Author | : Bernd W. Rautenstrauß |
Publisher | : Springer |
Total Pages | : 494 |
Release | : 2012-02-03 |
ISBN-10 | : 3642564054 |
ISBN-13 | : 9783642564055 |
Rating | : 4/5 (54 Downloads) |
Book excerpt: Fluorescence in situ hybridization (FISH) has been developed as a powerful technology which allows direct visualisation or localisation of genomic alterations. The technique has been adopted to a range of applications in both medicine, especially in the areas of diagnostic cytogenetics, and biology. Topics described in this manual include: FISH on native human tissues, such as blood, bone marrow, epithelial cells, hair root cells, amniotic fluid cells, human sperm cells; FISH on archival human tissues, such as formalin fixed and paraffin embedded tissue sections, cryofixed tissue; simultaneous detection of apoptosis and xpression of apoptosis-related genes; comparative genomic ybridization; and special FISH techniques.