X-ray Holography at Lawrence Livermore National Laboratory
Author | : |
Publisher | : |
Total Pages | : 5 |
Release | : 1990 |
ISBN-10 | : OCLC:727303694 |
ISBN-13 | : |
Rating | : 4/5 (94 Downloads) |
Book excerpt: The x-ray holography program at the Lawrence Livermore National Laboratory has two principal goals: (1) the development of x-ray diffraction techniques for DNA sequence analysis and (2) the development of x-ray laser holography for structural analysis of intact biological cells and organelles. DNA sequence analysis will be accomplished by applying x-ray diffraction techniques to determine the ensemble average of the sequence of labels along the individual elements of crystalline DNA. X-ray laser holographic imaging will be accomplished by applying three dimensional x-ray holography to elucidate the structure of few hundred angstrom objects such as 300 Å chromatin fibers, nuclear pores and nucleic acid replication complexes in living cells. Existing laboratory x-ray lasers will be utilized to produce flash x-ray holograms of the biological structures.