The treatment of patients with advanced malignancies has undergone remarkable change in the last few years. While in the past decisions about systemic therapy w

Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the deve

Highly Commended in the category of Oncology at the British Medical Association Awards 2019 The accessible guide to the principles behind new, more targeted dru

This work covers the pathophysiology of cancer, exploring the difficulty of optimal treatment due to the complexity and diversity of cancer types. The search fo

From its introduction, oncological chemotherapy has been encumbered by poor selectivity because antiproliferative drugs are often toxic not only to tumor cells