New Rapid-acting Antidepressants
Author | : Kenji Hashimoto |
Publisher | : Springer Nature |
Total Pages | : 152 |
Release | : 2021-10-22 |
ISBN-10 | : 9783030797904 |
ISBN-13 | : 3030797902 |
Rating | : 4/5 (04 Downloads) |
Book excerpt: This book discusses new candidates for rapid-acting antidepressants, such as (R)-ketamine, (2R,6R)-hydroxynorketamine, scopolamine, mGluR2/3 antagonists and AMPA receptor agonists. There are serious limitations to currently available antidepressants, such as delayed onset and low rates of efficacy. The discovery that a single dose of ketamine, an NMDAR antagonist, can produce rapid antidepressant effects that are sustained has led to new research in this area. In this volume, a variety of novel pharmaceutical treatments are examined. This volume would be useful to both researchers and clinicians who work in the field of pharmacology, specifically CNS drug treatments.