Atlas of Tumor Pathology of the Fischer Rat

Book excerpt: This book provides a comprehensive resource of the most recent findings on the pathogenesis and pathology in the Fischer rat. Each chapter, adequately illustrated with light and electron photomicrographs, deals with a specific organ system. It includes a summary of the spontaneous neoplasms found in over 5,000 untreated control animals as well as a detailed, step by step necropsy procedure completely illustrated by photographs. It refers to a listing of common and rare tumors associated with the administration of various environmental agents obtained from over 200 carcinogenesis bioassays of the National Cancer Institute and National Toxicology Program. This work also reveals detailed information on spontaneous occurrence and the induction of neoplasms. Scientists involved in the evaluation of toxicological and carcinogenesis bioassays and investigators conducting basic and applied carcinogenesis research will find this atlas indispensable.