This book integrates recent methodological developments for calculating the sample size and power in trials with more than one endpoint considered as multiple p

Praise for the Second Edition: "... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and careful

Delineates the statistical building blocks and concepts of clinical trials.

Drawing on various real-world applications, Sample Sizes for Clinical Trials takes readers through the process of calculating sample sizes for many types of cli

Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps